A legend has been lost in fashion.

Designer Virgil Abloh, the artistic director of Louis Vuitton’s menswear collection and the CEO of the Off-White label, has died at the age of 41 after privately battling “a rare, aggressive form of cancer, cardiac angiosarcoma,” a statement read on his Instagram on Sunday, Nov. 28.

“We are devastated to announce the passing of our beloved Virgil Abloh, a fiercely devoted father, husband, son, brother, and friend,” a message posted on the designer’s Instagram account stated. His loving wife is his survivor. Shannon AblohHis children Lowe AblohAnd Grey AblohHis sister Edwina AblohHis parents NeeAndEunice AblohAnd many other dear friends, colleagues, and family.”

The statement states that Virgil chose to continue his struggle privately after his 2019 diagnosis. He has been through many challenging treatments and oversees several important institutions, including fashion, art, culture, and education.